The exact original recording behind ayy mi pendejoo is not widely documented, so its popularity comes mainly from how it circulates online as a short Spanish-language reaction clip. The phrase itself is informal Spanish slang, used among friends as a teasing way to say someone is being foolish. That familiar, joking tone has helped it travel through meme edits, reaction videos and soundboard collections, where a brief voice line can carry the whole joke without needing subtitles or context.