The scream comes from iCarly, the Nickelodeon sitcom that ran from 2007 to 2012 starring Miranda Cosgrove as Carly Shay and Jennette McCurdy as Sam Puckett. Their loud, synchronized reactions were a running gag throughout the series and made perfect clip material once fans began isolating short moments for edits. As iCarly clips resurfaced on TikTok and YouTube, this particular dual scream became a reusable reaction sound for shock and panic, separate from its original scene but still tied to the show's chaotic energy.