The line comes from a video by French creator SienceEncoder about chemtrails, in which a character called Radis Irradié reacts to a supposed victim with the dismayed cry 'ho non, il est mort'. Lifted from that context, the seven-second outburst found a second life on French-language soundboards as a ready-made reaction to any on-screen death, literal or figurative. The voice sounds genuinely devastated, which makes the exaggeration funnier when it lands on something trivial, and it remains a favourite among French meme editors wanting a dramatic death gag with local flavour.