The line comes from Peter Parker in Marvel's Avengers: Infinity War (2018), during the film's famous dusting scene with Tony Stark. Online, it spread as a reaction meme because the delivery is emotional and instantly recognizable, even out of context. Creators use it for ironic overreactions, fake death edits, and sudden-loss jokes across short videos and compilations. It is often paired with sad violin or other dramatic cues to heighten the sense of collapse.