The laugh comes from J K Simmons as J Jonah Jameson, the Daily Bugle editor in Sam Raimi's Spider-Man films, where his explosive laughing at Peter Parker became one of the trilogy's most quoted scenes. Clipped and shared as a reaction sound, it spread through meme edits and soundboards alongside other mocking laughs like Nelson's HA-HA! It remains popular because the performance is instantly recognisable even without the picture, turning a short audio clip into shorthand for finding something laughably wrong, naive, or completely unserious.
About this sound
J Jonah Jameson bursting into loud mocking laughter from Spider-Man, used as a reaction sound for jokes, disbelief and roasting moments online.
This is J Jonah Jameson throwing his head back and erupting into a long, over the top belly laugh, the kind he aims at Peter Parker in Spider-Man. The laugh starts smug and keeps building, getting louder and more mocking with each burst, which makes it sound less like amusement and more like a put down. That exaggerated delivery is why it lands so well as a reaction, instantly telling the viewer that whatever just happened is ridiculous, unbelievable, or not to be taken seriously at all.