La Carita Mirtha circulates mainly in Spanish-speaking meme communities as a short reaction sound for cute and cheeky facial expressions. It is shared on soundboards and in short-form video edits, where creators use it to punctuate a close-up, a selfie or a playful reaction. Its appeal comes from its warm, familiar tone and its instant recognisability in that context, rather than from a long clip or a complex joke. Because the moment is brief and easy to place, it keeps appearing in new edits and reaction compilations.