The phrase is closely associated with American rapper Lil Boosie, whose outspoken interviews and social media clips have made c'mon mane a recognisable piece of internet slang. Short audio snippets of the line began circulating on soundboards and in meme edits, where it was reused as a quick reaction sound for disbelief, frustration, and playful disapproval. Because the delivery is instantly recognisable and easy to place over almost any surprising moment, it has stayed popular with creators long after the original clips first spread online.