MC Fioti first released Bum Bum Tam Tam in 2017 through KondZilla, and its flute sample made it one of Brazilian funk's biggest exports. In January 2021, during the Covid vaccine rollout in Brazil, he reworked it as Vacina Butantan with the Butantan Institute in Sao Paulo, which produces CoronaVac. The playful remix was shared widely on social media to encourage vaccination, turning a serious campaign into a pop culture moment. The short vocal excerpt continues to circulate in memes long after the campaign.