The phrase o que é isso is everyday Portuguese for what is that, widely understood in Brazil and Portugal as a spontaneous question when something looks odd. As a standalone clip it circulates on soundboards and in short video edits detached from any single original source, which is why its exact recording origin is unclear. Its popularity comes from how portable it is: the short length, clear questioning intonation and familiar wording let creators reuse it across memes, reaction videos and messaging apps without needing any extra context to explain the joke.
About this sound
Short Portuguese voice clip of someone asking o que é isso, meaning what is that, used as a confused reaction sound in memes, edits and group chats.
This is a very short spoken reaction lasting just over a second, featuring a single voice asking o que é isso in Portuguese with a tone of genuine surprise and confusion. The delivery is quick and slightly rising at the end, as if the speaker has just seen something strange and cannot process it. There is no music or added effect behind the voice, which makes the question feel immediate and human. Viewers instantly understand the reaction even without speaking Portuguese, and that clarity is why the clip works as a fast punchline for weird or unexpected moments.