The line comes from the 1980 parody Airplane, released as Flying High in many countries, in a cockpit scene between Ted Striker and Dr Rumack, played by Leslie Nielsen. Striker says the line in disbelief, and Rumack replies that he is serious and not to call him Shirley, a pun that became one of the film's most quoted jokes. The exchange has been repeated in quote lists, reaction videos and edits for decades, with the first half now used on its own as shorthand for stunned disbelief.