The Binding of Isaac is an indie roguelike video game first released in 2011, in which Isaac flees into a monster-filled basement to escape his mother, Mom, who becomes one of the game's recurring bosses. Her voice calling his name has become one of the game's most recognisable audio moments because it turns a simple word into a threat. Clips of the line have spread through gaming soundboards, YouTube edits, and TikTok videos, where creators reuse it to signal danger, a boss fight, or a dark joke about overbearing parents.