Pinky and the Brain began as a recurring segment on Animaniacs before becoming its own animated series in the 1990s, built around two laboratory mice with opposite personalities. Each episode ended with Brain's nightly plan to take over the world, a running joke that turned the line into one of animation's most quoted catchphrases. The Spanish dub, known as Pinky y Cerebro, kept that same scheming tone for Latin American and Spanish audiences. Clips of the exchange still circulate as memes because the setup is instantly understood, even without the full episode.