The clip is best understood as a generic cartoon disappearance effect rather than a line from a named show or film. Short poof sounds like this have long been used in animation and comedy edits to signal that a ghost, magician or prankster has slipped away unseen. On soundboards it circulates as a quick, reusable gag for vanish moments, reaction videos and short-form clips, where its brevity matters more than any single origin. That flexibility is why it keeps appearing whenever a creator needs an instant, light-hearted disappearance.