Put it at the end of a short exchange, right after the obvious statement, then follow it with Awkward Crickets Sound Effect for the next beat, and save Yooooo Reaction Sound for a louder follow-up from another character.
About this sound
This is a very short Spanish spoken clip, lasting under three seconds, in which a man snaps the line “ya lo sé, maricón” in a sharp, annoyed voice. It feels fed-up and confrontational, like a coworker cutting off a pointless explanation, and it lands as an instant, blunt put-down for anyone stating the obvious.