Place it at the end of a joke or fail edit, after the setup has landed, then follow it with the Anime Ahh sound for a second wave of laughter, or cut to the Womp Womp Fail sound when the laugh is really at someone's expense.
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This clip is a long, high-pitched anime-style laugh that builds and keeps going for about twelve seconds, with a playful, exaggerated delivery. It feels gleeful and unhinged, the kind of laugh that makes a joke feel bigger and a fail feel funnier, landing best when the reaction needs to be louder than the moment itself.