Place it at the exact reveal of the failure, after a sudden suspense hit builds the tension and before a sad violin button carries the aftermath. A no no wait wait clip works just before it when someone tries to stop the mistake.
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A short two-second voice clip of someone stretching out a desperate 'NOOOOO' in pure despair, loud and drawn out rather than quick. It gives a listener that sinking, over-the-top feeling of loss and disbelief, like watching a plan collapse at the very last second with no way to stop it happening.