Place it at the exact reveal in a short edit, after a normal reaction line and before a cutaway gag. Follow it with the scream meme for panic, or precede it with the bruh soundboard button when the setup needs a deadpan beat first.
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This is a sub-second voice clip of a man bluntly saying the words man flesh in a low, guttural delivery. It lasts under a second and lands as a single punchy line with no build-up. Hearing it feels gross, feral and darkly funny, like a villain announcing dinner, which is why it works as an instant creepy punchline.