Toxic was released in 2004 as a single from Britney Spears' album In the Zone and became one of her signature hits, built around a distinctive Bollywood inspired string sample. Its chorus and title word stayed in pop culture through radio, film and countless online edits. As short form video grew, creators began isolating the sung word as a ready made label for drama and bad behaviour, turning a chart chorus into a reaction sound that needs no explanation for anyone who knows the song.