Place it at the very end of a short edit as the final reaction, after the setup line has finished. Follow it with a laugh moment like the Kiko laugh to close the bit, rather than stacking another reaction clip on top.
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This is a short 3.2-second voice clip built around a drawn-out 'oh hell naww' reaction, repeated for extra disbelief. It lands as funny and incredulous, the kind of stunned refusal you feel when something is so wrong you have to laugh before you can even argue with it.