Place it right after the cute reveal in your edit, letting the reaction close the moment before the next scene begins. Follow it with clapping to turn the reaction into applause, and keep it ahead of any louder joke so the moment is not lost.
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This three-second clip captures Agnes, the youngest girl in Despicable Me, squealing in Portuguese that something is so fofinho. Her high, delighted voice makes the line feel warm and playful, like a burst of pure excitement over something tiny and lovely. It comes from the animated film Meu Malvado Favorito, where Agnes reacts to something she finds irresistibly sweet.