Doflamingo, known to fans as Doffy, is a major antagonist in One Piece, and his distinctive laugh became one of his most recognisable traits among viewers. Clips of the laugh circulated through anime edits, reaction videos and meme compilations, where it was reused to signal arrogance, cruelty or a twist going exactly as a villain planned. Because the sound is instantly tied to a confident, scheming character, it still works as shorthand for an evil reveal even for viewers who have not followed the full series.