Put it at the end of a fail sequence, after the mistake is clear, and lead into it with Dramatic Dun Dun Dun to set up the payoff, then follow it with SpongeBob Fail for a second beat.
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This is the GTA V Wasted game-over sting, a roughly eight-second dramatic low hit with a gloomy, slowed-down feel that lands like a final blow. It feels instantly deflating and funny, turning a mistake into total defeat. It comes from Grand Theft Auto V, released by Rockstar Games in 2013, where it plays over the red WASTED screen when the player dies.