Place it right at the reaction beat, after the line that sets it up and before the reply lands. Follow it with the Mayuri Tuturu sound for a second cute voice hit, or switch to the Anime Ahh sound when the scene needs a bigger reaction.
关于此声音
This is a very short voice clip built around Neco-Arc, the tiny cat-like anime character, delivering the playful Yuri Yuru line in a high, chibi style. It lasts just over a second, so the hit is instant. The feeling is light, silly and affectionate, like a cute interruption that breaks tension without needing any setup or explanation.