Nossa, que isso is a common Brazilian Portuguese expression of surprise, roughly translated as wow, what is that, and it has become a familiar reaction sound in online humour rather than a quote from one identifiable film or television show. Brazilian creators use the short exclamation in memes, reaction videos and short-form edits when something looks absurd, impressive or hard to believe. Its appeal is its immediacy: the phrase is short, expressive and easy for Portuguese-speaking audiences to recognise instantly, which keeps it circulating whenever a new surprising clip needs a quick, human reaction.