The scream comes from SpongeBob SquarePants, the long-running Nickelodeon cartoon, and belongs to Sheldon J. Plankton, the scheming owner of the Chum Bucket who is constantly trying to steal the Krabby Patty secret formula. The clip is labelled from the episode New Leaf, in which Plankton briefly tries a different approach to life. Once separated from the episode, the yell began circulating on meme soundboards and in short video edits, where fans recognised it instantly as Plankton at his most frustrated. Its lasting appeal is that contrast between a tiny villain and an enormous, theatrical outburst.