Put it near the end of a fail or reaction edit, after the setup has played out and the audience knows what went wrong. Start with a shocked sound to sell the surprise, then let this laugh carry the payoff, and finish with Oh No No No Laugh if you want the joke to keep escalating.
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This is the full ten-second take of a man laughing hard, with loud, rolling laughter that keeps building instead of fading after one burst. It feels wildly funny and hard to take seriously, like a reaction that has completely lost control. The laugh lands instantly, turning an awkward pause or a bad decision into something that feels absurd and over the top.