The clip comes from Metal Gear Solid V: The Phantom Pain, released in 2015, and is tied to the widely quoted line about a lust for revenge from its trailers and story scenes. Fans isolated the extended who as a standalone reaction and shared it across forums, video edits and soundboards. Its fame grew because the serious, cinematic delivery clashes with the silly situations it now scores. It remains a go-to shorthand for theatrical disbelief in gaming communities.
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A drawn-out WHOOOO shout from Metal Gear Solid V, taken from the famous lust for revenge line and used as a confused reaction in memes and edits.
This is a short, stretched-out shout of who, delivered with intense, almost theatrical anger and confusion. The voice rises and holds the vowel far longer than a normal question, turning a simple word into a dramatic accusation. It sounds like someone demanding an answer they already dread hearing. That over-the-top delivery is why it lands as funny out of context, especially when it is dropped over an unrelated clip. The tension in the voice makes even a minor reveal feel like a major betrayal or plot twist.