This clip comes from Dragonzball PeePee, the Dragon Ball parody series made by Oney Videos, where familiar anime action is retold with deliberately absurd, crude humour. The shouted line works because it is a universal reaction, not tied to one scene, so it was lifted from the episode and shared on soundboards as a standalone reaction. Creators keep returning to it for the same reason short catchphrases survive online: it is instantly recognisable, takes barely a second to land, and can punctuate almost any moment of exaggerated audio discomfort.