Place it at the end of a short setup showing someone missing an obvious joke, then follow it with the Bruh sound for the next beat and the Emotional Damage sound if the embarrassment keeps escalating.
關於此聲音
This is a brief spoken meme line, lasting about three seconds, built around the phrase you need a high IQ to get E. The delivery feels smug and teasing, like a joke aimed at someone who missed the point, and that mock-superior attitude is what makes it funny rather than clever.