The line comes from Gex 2, also released as Gex Enter the Gecko, the 1998 sequel in Crystal Dynamics platform series starring the wisecracking gecko Gex. Gex was known for constant pop culture one liners delivered while exploring TV themed worlds, and short lines like this survived because they work out of context. Clipped from the in game chatter, the phrase later circulated on soundboards as a standalone insult and reaction, separate from the level or cutscene where players first heard it.