The line comes from Italian slang rather than a formal catchphrase, with sti cazzi used in everyday speech to brush something off as unimportant. Clips like this travel well because the meaning survives even for listeners who only catch the tone, and Italian meme pages and video editors have reused short television dialogue as instant reaction audio for years. Its staying power comes from that brevity: at just over a second, it fits a cut, a caption, or a reply without needing context, setup, or translation.