Place it as the main reaction after the visual payoff in your edit, and for a layered joke follow it with the laughing dog meme for a second wave, or precede it with Nelson's Ha-Ha! for a shorter teasing lead-in.
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This clip is Mimon Baraka laughing out loud for about thirteen seconds, with the laugh carrying the whole recording as a single reaction take. It feels openly amused and contagious, the kind of unrestrained laughter that makes a funny moment seem even funnier to everyone listening along with it in the room.