Put it at the end of a visual gag, just as the subject exits the frame, then follow with the Goofy Ahh Running Sound for a chase and the Cartoon Slip Sound Effect for a clumsy landing.
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This two-second vocal clip captures Neil deGrasse Tyson saying “nyoom” with an over-the-top, teasing delivery. It feels cartoonish and light, instantly suggesting speed and something shooting off screen, with a nerdy charm that makes the silliness land. It became known through short-form meme edits and reaction posts that used the word for sudden movement and space jokes.