Pee-yew is a classic comic expression of disgust, long used in cartoons, comedy sketches and everyday speech to signal that something smells bad. Online, the short spoken version became a handy reaction clip for memes, short videos and soundboards, where a single word can deliver the whole joke without explanation. It is often paired with gross-out moments, food fails and messy reveals, and it sits alongside other gross-out reactions like Eww brother eww for creators who want an instant, light-hearted response to something unpleasant.