This clip is listed on soundboards under Deadpool, and its popularity comes mainly from Spanish-language meme and chat culture rather than a single famous scene. The phrase is a blunt, colloquial way of calling something absurd or ridiculous, so creators reuse it as a quick reaction to fails, plot twists and unbelievable messages. Shared widely as a short downloadable reaction sound alongside other short reaction sounds like Bruh meme, it stays useful because the tone is instantly clear and the clip is short enough to drop into almost any edit without slowing it down.