Place it after an anime clip or recommendation, then follow it with Bruh Meme for a second reaction and Fail Sound Meme if the recommendation keeps going. It also works before It Was At This Moment He Knew when a debate is about to turn against the anime fan.
About this sound
This short clip is a single blunt spoken line declaring that anime belongs in the trash, delivered in a flat, dismissive voice over about three and a half seconds. It lands as a deliberately rude joke, more teasing than angry, and works best as a quick put-down when anime comes up in conversation.