Place it as the final beat after the argument setup, then follow with a funny ha ha laugh sound for the reaction and a ba dum tss drum sting if you want the scene to end like a sitcom bit.
About this sound
This 4.8-second music clip is the hook from Black Eyed Peas' 'Shut Up,' with polished pop and hip-hop energy built around a blunt shut-up command. It feels fed-up, dismissive and theatrically annoyed, like an argument cut short. It comes from their 2003 album Elephunk.