The line riffs on Muscle Man's running gag from Regular Show, the Cartoon Network series that ran from 2010 to 2017, where he constantly asks 'Do you know who else...' before a 'my mom' punchline. This dementia version swaps the expected ending for a more absurd twist and spread as a short meme clip on social video apps. Its familiarity comes from years of fans quoting the setup in comments and remixes, keeping the format alive long after the show ended.