Place it at the climax of a build-up, after the annoyances have stacked up and just before the reaction shot. Let Awkward Crickets Sound Effect follow the line to hold the beat, then cut straight to the next scene without adding another reaction.
About this sound
This is a 27-second spoken Portuguese line, “eu não estou suportando mais,” delivered in a tired, strained voice that sounds worn down rather than shouted. It carries plain frustration and emotional overload, the feeling of reaching a limit after too much piling up at once. It circulates as a Brazilian meme reaction, reused whenever everyday stress needs an instantly recognisable voice of exasperation.