This sound comes from the scientist voice lines in Half-Life, Valve's 1998 first-person shooter. The game's frightened lab scientists became memorable for their anxious delivery, and short scream clips like this spread through game edits, machinima, and meme videos as compact panic reactions. It is still used because the old PC game audio has a distinctive texture that reads immediately, especially in retro gaming content or clips that need a quick burst of alarm similar to a FNAF Jumpscare Scream.