Put it right after the confusing claim in your edit, then follow it with Bruh for a flat dismissal or Emotional Damage when the take actually hurts. Use it as the turning point before the punchline, not as the opening, so the reaction earns its place.
About this sound
This is a roughly 4.6-second spoken clip of Hbomberguy asking, in a sharp, incredulous voice, what the hell you are talking about. It lands as pure baffled disbelief, funny because it sounds like a direct challenge to a claim that makes no sense. The line is delivered as a reaction to nonsense, turning confusion into a blunt, memorable call-out.