Place it in the middle of a reaction edit, right after the triggering line, then follow it with the nope meme sound as the final response before cutting to the next scene or replay.
About this sound
The Hashran sound is a 15-second electronic beep that holds as a sustained tone rather than a short blip. It turns a normal exchange tense and deliberately awkward, creating confusion and comic discomfort that lingers while the beep continues over the moment.