Place it at the climax of a failed trade or unwanted gift reveal, after a simple setup clip and before any reaction shot. Pair a Nope first to set up the refusal, then let this clip deliver the peak rejection, and finish with Inception Horn Sound Effect for a dramatic beat after the outburst.
About this sound
Cave Johnson delivers a loud, escalating shout lasting about three and a half seconds, refusing a pile of lemons and demanding to know what anyone expects him to do with them. The delivery feels furious, incredulous and absurdly overblown, far bigger than the complaint behind it. It comes from Portal 2, where J. K. Simmons voices the Aperture Science founder in a pre-recorded message.