The line comes from Grand Theft Auto: Vice City, the 2002 Rockstar game set in a fictional 1980s Miami-inspired city. Its short voice clips have long circulated separately from gameplay as reaction sounds, shared in edits, streams and soundboards. This quote survived because the name Mario and the self-directed warning are easy to recognise out of context, even for viewers who have not played the game. It is now used less as a reference to a specific scene and more as a standalone cue for calming down.