Place it as the punchline at the end of a prank setup, after a Vine Boom sets up the scene, then follow it with a classic fart for a second hit before the reaction shot lands.
About this sound
This is a long hand fart lasting about seven seconds, a run of rasping, squeaky bursts made by pressing a cupped hand against skin to mimic a fart. It sounds deliberately crude and overdone, stretching a quick gag into something awkward and hard to ignore. It gives listeners a silly, lowbrow laugh, the kind that breaks a serious moment, and comes from IAmSp00n's long version of the gag.