Place it right after the mistake lands in the edit, then follow it with the Windows XP Error sound to underline the failure, and hold the Metal Gear Alert sound for the moment the consequences start.
About this sound
This is the Kool-Aid Man voice repeating oh no, no, no, no in an urgent shout that runs for about eleven seconds. The repetition makes the panic feel bigger with each word, turning a small mistake into a full disaster in the listener's head. It works as a quick, over-the-top reaction to bad news, a failed plan or a moment that suddenly goes wrong.