The sound comes from Pantry Pirate, a Pluto cartoon released on 27 December 1940, where Pluto's attempt to raid the pantry ends in classic slapstick trouble. The exaggerated sneeze was later circulated as a stock cartoon effect, catalogued in professional sound libraries under descriptions of a man sneezing rapidly. That library life helped it outlive the short itself, as editors reused the burst and crash for cartoons, comedy edits and reaction videos. Its old school timing is why it still works for modern meme cuts.