The greeting comes from MrBeast, the YouTube creator Jimmy Donaldson, who opens many of his challenge and stunt videos with a rapid 'What's up guys' before explaining the premise. As his channel grew into one of the platform's biggest, the intro became instantly recognisable to viewers around the world. Clips of it were reused in edits, memes and parodies, often to signal that an over-the-top challenge was about to begin. It remains popular because it instantly sets a familiar, high-energy YouTube tone in just two seconds.