Place it as the fake official reply after a setup line, then follow with the we do not care sound for a dismissive turn, or swap that order and let it close a short reaction chain in a meme edit.
About this sound
This is a 3.3-second voice clip of the Obama character as portrayed in Family Guy, lifted from a Cold Ones Etsy video. It lands as a deadpan, out-of-place presidential drop that feels funny and slightly surreal, turning an ordinary reaction into a cartoon political cameo.