Muscle Man is a main character from Regular Show, the Cartoon Network animated series created by J.G. Quintel that ran from 2010 to 2017 and was voiced by Sam Marin. His running gag was starting a joke with You know who else and answering My mom, which became one of the show's most quoted bits. Clips of the line spread on YouTube, TikTok and meme soundboards, where the short isolated punchline is now used as a standalone reaction to mock setups and roasts.